Description

2-Fluoro-5-Nitrophenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in the unique reactivity of the boronic acid group combined with the electronic directing effects of the fluorine and nitro substituents, enabling precise cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides requiring specific fluorinated aromatic scaffolds.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-Nitrophenylboronic Acid
CAS No.	819849-20-2
Molecular Formula	C6H5BFNO4
Molecular Weight	184.92 g/mol
Synonyms	(2-Fluoro-5-nitrophenyl)boronic acid; 2-Fluoro-5-nitrobenzeneboronic acid; B-(2-Fluoro-5-nitrophenyl)boronic acid; 5-Nitro-2-fluorophenylboronic Acid; Boronic acid, B-(2-fluoro-5-nitrophenyl)-; 2-Fluoro-5-nitrophenyl-B(OH)2; 819849-20-2; FC6H3(NO2)B(OH)2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.