Description

4-Amino-3-Fluorophenylboronic Acid, Pinacol Ester is a high-value, protected boronic acid derivative, essential for modern synthetic chemistry. This compound is a critical building block for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds under mild conditions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or precursor in the synthesis of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, inhibitors, and bioconjugation reagents due to its stable, protected boronate group.
• Catalyst Ligand Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Amino-3-Fluorophenylboronic Acid, Pinacol Ester
CAS No.	819058-34-9
Molecular Formula	C12H17BFNO2
Molecular Weight	237.08 g/mol
Synonyms	4-Amino-3-fluorobenzeneboronic acid pinacol ester; (4-Amino-3-fluorophenyl)boronic acid pinacol ester; 3-Fluoro-4-aminophenylboronic acid pinacol ester; 4-Amino-3-fluorophenyl-Bpin; 4-Amino-3-fluoro-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 2-(4-Amino-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(4-Amino-3-fluorophenyl)boronic acid pinacol ester; NSC 855263
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Fluorophenylboronic Acid, Pinacol Ester is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.