Description

(3E)-1,1,1-Trifluoro-3-Methyl-4-(4-Methylphenyl)-3-Buten-2-Imine is a high-value, specialized fluorinated imine building block, offering a unique trifluoromethylated structure for advanced synthetic chemistry. This compound is critical for introducing fluorine atoms and imine functionality into target molecules, enabling the development of novel materials and bioactive compounds with enhanced properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in areas like oncology, CNS disorders, and anti-infectives.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Precursor: Serves as a building block for advanced polymers, liquid crystals, or organic electronic materials requiring specific fluorine content.
• Chemical Synthesis Reagent: Employed in organofluorine chemistry for constructing complex molecules via imine chemistry and subsequent transformations.
• Academic & R&D Laboratories: Utilized in methodological studies and discovery chemistry for exploring new fluorination strategies and reaction pathways.

Basic Information

Item	Detail
Product Name	(3E)-1,1,1-Trifluoro-3-Methyl-4-(4-Methylphenyl)-3-Buten-2-Imine
CAS No.	817164-11-7
Molecular Formula	C12H12F3N
Molecular Weight	227.23 g/mol
Synonyms	(E)-1,1,1-Trifluoro-3-methyl-4-(p-tolyl)but-3-en-2-imine; (3E)-1,1,1-Trifluoro-3-methyl-4-(4-methylphenyl)-3-buten-2-one imine; 4-Methyl-α-(trifluoromethyl)cinnamylideneimine; Trifluoro-3-methyl-4-(4-methylphenyl)-3-buten-2-imine; (E)-4-Methyl-α-(trifluoromethyl)cinnamaldehyde imine; 817164-11-7; p-Tolyl trifluoromethyl butenimine
EINECS	Contact for details

Quality Control

Our (3E)-1,1,1-Trifluoro-3-Methyl-4-(4-Methylphenyl)-3-Buten-2-Imine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.