Description

4-Fluoro-2-Methylphenylboronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its primary value lies in its stability and reactivity as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated and methylated aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	4-Fluoro-2-Methylphenylboronic Acid, Pinacol Ester
CAS No.	815631-56-2
Molecular Formula	C₁₃H₁₈BFO₂
Molecular Weight	236.09 g/mol
Synonyms	4-Fluoro-2-methylbenzeneboronic acid pinacol ester; 2-Methyl-4-fluorophenylboronic acid pinacol ester; (4-Fluoro-2-methylphenyl)boronic acid pinacol ester; 4-Fluoro-o-tolylboronic acid pinacol ester; Pinacol (4-fluoro-2-methylphenyl)boronate; B-(4-Fluoro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 815631-56-2; 4-Fluoro-2-methylphenyl-Bpin
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.