Description

(S)-Allyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-Aminohexanoate Hydrochloride is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block, enabling the controlled introduction of the (S)-2,6-diaminohexanoic acid (lysine analog) residue with orthogonal protecting groups for Fmoc-based solid-phase strategies. It is primarily required by research institutions and pharmaceutical developers working on novel therapeutic peptides, protein engineering, and biochemical probes where precise stereochemistry and side-chain functionality are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate in the Fmoc/t-Bu strategy for the site-specific incorporation of a protected lysine analog.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation & Probe Development: The allyl ester protecting group allows for selective deprotection, facilitating the creation of labeled peptides or peptide-drug conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptides.
• Academic Research: Utilized in studies of protein-protein interactions, signal transduction pathways, and structural biology.

Basic Information

Product Name	(S)-Allyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-Aminohexanoate Hydrochloride
CAS No.	815619-80-8
Molecular Formula	C24H27N2O4 • HCl
Molecular Weight	452.95 g/mol
Synonyms	Fmoc-Lys(Alloc)-OH • HCl; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(allyloxycarbonyl)amino)hexanoic acid hydrochloride; Nα-Fmoc-Nε-Alloc-L-lysine hydrochloride; Fmoc-Lys(Alloc)-OH hydrochloride; Nα-Fmoc-Nε-allyloxycarbonyl-L-lysine hydrochloride; Alloc-Lys(Fmoc)-OH • HCl; Fmoc-L-Lys(Alloc)-OH hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Allyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-Aminohexanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the exacting standards required for peptide research and cGMP starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.