Description

1H-Imidazole-4-Carbonitrile, 2-Nitro- (9Ci) is a specialized heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a nitrile and a nitro group on the imidazole core, makes it a valuable precursor for the development of novel pharmaceuticals and agrochemicals. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, catalysts, and functional polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based probes for studying enzyme function and protein interactions.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic compounds.

Basic Information

Product Name	1H-Imidazole-4-Carbonitrile, 2-Nitro- (9Ci)
CAS No.	813462-49-6
Molecular Formula	C4H2N4O2
Molecular Weight	138.09 g/mol
Synonyms	2-Nitro-1H-imidazole-4-carbonitrile; 2-Nitroimidazole-4-carbonitrile; 4-Cyano-2-nitroimidazole; 1H-Imidazole-4-carbonitrile, 2-nitro-; 2-Nitro-1H-imidazole-4-carbonitrile (9CI); 813462-49-6; 2-Nitro-4-cyanoimidazole
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carbonitrile, 2-Nitro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material consistency, from early-stage R&D to scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the compound's sensitivity, it is recommended to store under an inert atmosphere for long-term preservation and to minimize potential degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.