Description

1-n-Fmoc-3-Aminopyrrolidine is a high-purity, protected amino acid derivative essential for modern peptide synthesis. This compound serves as a critical building block, enabling the precise and efficient construction of complex peptide chains for pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the 3-aminopyrrolidine moiety into peptide sequences.
• Pharmaceutical Intermediate: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for protease inhibitors and other therapeutic peptides.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening and drug discovery.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or drug delivery systems.
• Agrochemical Research: Utilized in the synthesis of peptide-based pesticides and growth regulators.
• Academic & Contract Research: A fundamental reagent for universities and CROs conducting research in organic synthesis, medicinal chemistry, and chemical biology.

Basic Information

Product Name	1-n-Fmoc-3-Aminopyrrolidine
CAS No.	813412-37-2
Molecular Formula	C19H20N2O2
Molecular Weight	308.38 g/mol
Synonyms	Fmoc-3-Aminopyrrolidine; 3-Aminopyrrolidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminopyrrolidine; 1-Fmoc-3-aminopyrrolidine; 1-[(9-Fluorenylmethyloxycarbonyl)]-3-aminopyrrolidine; Nα-Fmoc-3-aminopyrrolidine; 3-Amino-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminopyrrolidine
EINECS	Contact for details

Quality Control

Our 1-n-Fmoc-3-Aminopyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) are available upon request, providing full transparency on purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.