Description

1H-Indene-5-Acetonitrile,2,3-Dihydro--α-,-α--Dimethyl-1-Oxo-(9Ci) is a high-purity, advanced pharmaceutical intermediate and fine chemical building block. This compound is valued for its unique indene-acetonitrile-oxo fused ring structure, which provides a versatile scaffold for synthesizing complex molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials. The product is supplied under strict quality control to ensure batch-to-batch consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its complex heterocyclic core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in the production of high-performance display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new organic reactions and heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals used in flavors, fragrances, and advanced polymers.

Basic Information

Product Name	1H-Indene-5-Acetonitrile,2,3-Dihydro--α-,-α--Dimethyl-1-Oxo-(9Ci)
CAS No.	812695-04-8
Molecular Formula	C14H15NO2
Molecular Weight	229.28 g/mol
Synonyms	2,3-Dihydro-α,α-dimethyl-1-oxo-1H-indene-5-acetonitrile; 5-(Cyanomethyl)-2,3-dihydro-α,α-dimethyl-1-oxo-1H-indene; α,α-Dimethyl-2,3-dihydro-1-oxo-1H-indene-5-acetonitrile; 1-Oxo-2,3-dihydro-α,α-dimethyl-1H-indene-5-acetonitrile; (812695-04-8); Indene-5-acetonitrile, 2,3-dihydro-α,α-dimethyl-1-oxo-; 5-Acetonitrile-2,3-dihydro-α,α-dimethyl-1-oxoindene
EINECS	Contact for details

Quality Control

Our 1H-Indene-5-Acetonitrile,2,3-Dihydro--α-,-α--Dimethyl-1-Oxo-(9Ci) is manufactured under a cGMP-compliant quality management system to ensure the highest standards of purity and traceability. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. Comprehensive Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.