Description

2-Bromo-1-Fluoro-4-Iodobenzene is a high-purity halogenated benzene derivative, a crucial multi-functional building block in advanced organic synthesis. Its unique combination of bromine, fluorine, and iodine substituents on the aromatic ring makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly via Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific halogen patterns are required for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in advanced electronic and display materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic methodologies and novel compound libraries.
• Fluorinated Compound Synthesis: The presence of both fluorine and iodine allows for selective functionalization, making it valuable for creating other fluorinated fine chemicals.

Basic Information

Product Name	2-Bromo-1-Fluoro-4-Iodobenzene
CAS No.	811842-30-5
Molecular Formula	C6H3BrFI
Molecular Weight	300.89 g/mol
Synonyms	1-Bromo-2-fluoro-4-iodobenzene; 2-Fluoro-4-iodobromobenzene; 4-Iodo-2-fluorobromobenzene; Benzene, 2-bromo-1-fluoro-4-iodo-; 2-Bromo-4-iodofluorobenzene; 2-Fluoro-1-bromo-4-iodobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Fluoro-4-Iodobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.