Description

1,2-Dibromo-3-Fluoro-Benzene is a halogenated aromatic compound of significant interest in advanced organic synthesis. Its value lies in its role as a versatile and reactive building block, offering multiple points for selective functionalization. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those containing fluorinated and brominated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers, such as liquid crystals or organic electronic materials.
• Organic Synthesis Building Block: Facilitates various transformations including Suzuki, Stille, and Negishi cross-coupling reactions due to the reactive bromine substituents.
• Fluorine Chemistry Studies: Acts as a model compound in research exploring the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Product Name	1,2-Dibromo-3-Fluoro-Benzene
CAS No.	811711-33-8
Molecular Formula	C6H3Br2F
Molecular Weight	273.89 g/mol
Synonyms	3-Fluoro-1,2-dibromobenzene; 1,2-Dibromo-3-fluorobenzene; 2,3-Dibromofluorobenzene; Benzene, 1,2-dibromo-3-fluoro-; 3-Fluorobenzene-1,2-dibromide
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3-Fluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.