Description

2-Pyrrolidinone, 1-Hydroxy-3-(2-Hydroxyethyl)-4-Phenyl-, (3R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined pyrrolidinone derivative. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, prized for its specific three-dimensional configuration. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), fine chemicals, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Serves as a precursor or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for novel synthetic routes.
• Ligand and Catalyst Development: Potential building block for creating novel chiral ligands and organocatalysts.

Basic Information

Product Name	2-Pyrrolidinone, 1-Hydroxy-3-(2-Hydroxyethyl)-4-Phenyl-, (3R,4R)-Rel- (9Ci)
CAS No.	811445-56-4
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	(3R,4R)-1-Hydroxy-3-(2-hydroxyethyl)-4-phenylpyrrolidin-2-one; rel-(3R,4R)-1-Hydroxy-3-(2-hydroxyethyl)-4-phenyl-2-pyrrolidinone; 1-Hydroxy-3-(2-hydroxyethyl)-4-phenyl-2-pyrrolidinone (3R,4R)-isomer; (R,R)-1-Hydroxy-3-(2-hydroxyethyl)-4-phenylpyrrolidin-2-one; 4-Phenyl-1-hydroxy-3-(2-hydroxyethyl)pyrrolidin-2-one (3R,4R)-form; 811445-56-4; A chiral 4-phenyl-2-pyrrolidinone derivative
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinone, 1-Hydroxy-3-(2-Hydroxyethyl)-4-Phenyl-, (3R,4R)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.