Description

(S,S)-1,2-Bis[(o-Tolyl)(Phenylphosphino)]Ethane, (S,S)-1,2-Ethanediylbis[(2-Methylphenyl)Phenylphosphine] is a high-value, chiral bisphosphine ligand essential for asymmetric catalysis. Its primary value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of optically pure intermediates. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing and scaling up chiral synthesis routes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component for enantioselective C-C bond formation (e.g., cross-coupling, allylic alkylation).li>- Key reagent in the synthesis of optically active natural products and complex molecules.
  • Used in academic and industrial research to develop new catalytic methodologies.
  • Potential application in the asymmetric synthesis of agrochemicals and flavors/fragrances.

Basic Information

Product Name	(S,S)-1,2-Bis[(o-Tolyl)(Phenylphosphino)]Ethane
CAS No.	810667-85-7
Molecular Formula	C30H30P2
Molecular Weight	452.50 g/mol
Synonyms	(S,S)-1,2-Ethanediylbis[(2-Methylphenyl)Phenylphosphine]; (S,S)-o-Tol-BIPHEP; (S,S)-2,2'-Bis(di-o-tolylphosphino)-1,1'-biphenyl (Note: This is a common misnomer for the ethane-bridged analog); (S,S)-Bis(o-tolylphenylphosphino)ethane; (S,S)-DTBPE; (S,S)-1,2-Bis(di-o-tolylphosphino)ethane; Chiral DTBPE Ligand
EINECS	Contact for details

Quality Control

Our production of (S,S)-1,2-Bis[(o-Tolyl)(Phenylphosphino)]Ethane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity, which is critical for catalytic performance. Each lot is characterized by NMR, HPLC, and specific optical rotation analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other relevant parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Optical Rotation	Contact for details
Solubility	Soluble in common organic solvents (Toluene, DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.