Description

1-Azabicyclo[3.2.0]Heptane-2-Carboxylicacid,7-Oxo-,(2R,5S)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam building block. This compound is a critical chiral intermediate in the synthesis of complex pharmaceutical molecules, particularly β-lactam antibiotics and other bioactive agents. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries seeking to introduce specific stereochemistry and functional complexity into their target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and commercial production of β-lactam antibiotics and other novel active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in asymmetric synthesis to construct complex, fused-ring systems with precise stereocontrol for medicinal chemistry programs.
• Process Chemistry: Serves as a starting material or advanced intermediate in the development and optimization of scalable synthetic routes under GMP conditions.
• Biochemical Research: Potential use as a precursor or inhibitor in enzymatic studies and proteomics research due to its lactam structure.
• Custom Synthesis: Foundation for the contract manufacturing of specialized, high-value fine chemicals and custom-designed molecular entities.

Basic Information

Item	Details
Product Name	1-Azabicyclo[3.2.0]Heptane-2-Carboxylicacid,7-Oxo-,(2R,5S)-(9Ci)
CAS No.	807613-68-9
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	(2R,5S)-7-Oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2R,5S)-7-Oxo-6-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2R,5S)-ABHCA; (2R,5S)-Bicyclic β-lactam carboxylic acid; (2R,5S)-Oxo-azabicycloheptane carboxylic acid; (2R,5S)-enantiomer of 7-Oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Stereoisomer of Penam carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.2.0]Heptane-2-Carboxylicacid,7-Oxo-,(2R,5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting identity, purity, and enantiomeric excess are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.