Description

(9H-Fluoren-9-Yl)Methyl (1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Carbamate is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily needed by the pharmaceutical, biotechnology, and advanced chemical research sectors for the development of therapeutic peptides, diagnostic agents, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediate: In the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: For the site-specific modification of peptides, proteins, and other biomolecules.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new lead compounds.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and interactions.
• Production of Custom Peptides: For contract research organizations (CROs) and CDMOs offering bespoke peptide synthesis services.

Basic Information

Item	Detail
Product Name	(9H-Fluoren-9-Yl)Methyl (1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Carbamate
CAS No.	805234-37-1
Molecular Formula	C25H22N2O4
Molecular Weight	414.46 g/mol
Synonyms	Fmoc-Phenylalanine-OH; Fmoc-Phe-OH; Fmoc-L-Phenylalanine; N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-phenylpropanoic acid; N-α-Fmoc-L-phenylalanine; Fmoc-Phenylalanine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl (1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and optical rotation, to ensure high chemical purity and chiral integrity suitable for sensitive peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.