Description

Tricyclo[3.2.1.02,4]Octane-3-Carboxylic Acid, 6-Oxo-, Ethyl Ester, (1R,2R,3R,4R,5R)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a sophisticated chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), where precise stereochemistry is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals requiring a rigid, polycyclic carboxylic acid ester framework.
• Academic Research: A valuable compound for methodological studies in organic synthesis and catalysis at universities and research institutes.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Octane-3-Carboxylic Acid, 6-Oxo-, Ethyl Ester, (1R,2R,3R,4R,5R)- (9Ci)
CAS No.	802911-54-2
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	(1R,2R,3R,4R,5R)-Ethyl 6-Oxotricyclo[3.2.1.02,4]octane-3-carboxylate; Ethyl (1R,2R,3R,4R,5R)-6-Oxotricyclo[3.2.1.02,4]octane-3-carboxylate; (1R,2R,3R,4R,5R)-6-Oxotricyclo[3.2.1.02,4]octane-3-carboxylic Acid Ethyl Ester; Tricyclo[3.2.1.02,4]octane-3-carboxylic acid, 6-oxo-, ethyl ester, (1R,2R,3R,4R,5R)-; Ethyl 6-oxotricyclo[3.2.1.02,4]octane-3-carboxylate (stereoisomer).
EINECS	Contact for details

Quality Control

Our Tricyclo[3.2.1.02,4]Octane-3-Carboxylic Acid, 6-Oxo-, Ethyl Ester, (1R,2R,3R,4R,5R)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.