Description

2,3,5,6-Tetrafluorobenzenemethanamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the tetrafluoro substitution pattern, which makes it a critical intermediate for developing novel active compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate fluorinated motifs into their molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the creation of fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis, enabling novel synthetic transformations.
• Functional Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric properties and chemical resistance.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	2,3,5,6-Tetrafluorobenzenemethanamine
CAS No.	89992-52-9
Molecular Formula	C7H5F4N
Molecular Weight	179.12 g/mol
Synonyms	(2,3,5,6-Tetrafluorophenyl)methanamine; 2,3,5,6-Tetrafluorobenzylamine; α-Amino-2,3,5,6-tetrafluorotoluene; 2,3,5,6-Tetrafluorobenzyl Amine; Benzenemethanamine, 2,3,5,6-tetrafluoro-; 89992-52-9; Tetrafluorobenzylamine
EINECS	Contact for details

Quality Control

Every batch of 2,3,5,6-Tetrafluorobenzenemethanamine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthesis. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.