Description

(R)-tert-Butyl 1-Hydroxybut-3-En-2-Ylcarbamate is a chiral, non-racemic building block of significant importance in modern organic synthesis. This compound serves as a key intermediate for the construction of complex molecules, particularly in the pharmaceutical sector where stereochemical purity is paramount. It is primarily utilized by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, especially in the development of protease inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can greatly influence biological activity and environmental safety.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers with high selectivity.
• Peptidomimetics Research: Serves as a building block for creating peptide analogs and peptidomimetics in medicinal chemistry programs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting point for custom synthesis projects requiring specific (R)-configured amino alcohol derivatives.

Basic Information

Product Name	(R)-tert-Butyl 1-Hydroxybut-3-En-2-Ylcarbamate
CAS No.	89985-86-4
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonylamino)but-3-en-2-ol; (R)-N-Boc-1-amino-3-buten-2-ol; (R)-tert-Butyl (1-hydroxybut-3-en-2-yl)carbamate; (2R)-1-[(tert-Butoxy)carbonyl]amino-3-buten-2-ol; (R)-Boc-3-buten-2-amine-1-ol; (R)-2-(Boc-amino)-3-buten-1-ol; (R)-N-(tert-Butoxycarbonyl)-3-buten-2-amine-1-ol
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-Hydroxybut-3-En-2-Ylcarbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral HPLC), to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.