Description

4-Amino-5-Oxo-Proline Methyl Ester is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical actives and bioactive peptides. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other complex therapeutic molecules.
• Peptide Chemistry: Used in the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics to introduce specific structural motifs.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme substrate research.
• Fine Chemical Synthesis: A versatile building block for constructing heterocyclic compounds and other specialized organic structures.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel, bioactive crop protection agents.

Basic Information

Product Name	4-Amino-5-Oxo-Proline Methyl Ester
CAS No.	89971-20-0
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	Methyl 4-amino-5-oxopyrrolidine-2-carboxylate; 4-Amino-5-oxo-L-proline methyl ester; (S)-Methyl 4-amino-5-oxopyrrolidine-2-carboxylate; 5-Oxo-4-aminoproline methyl ester; L-4-Amino-5-oxoproline methyl ester; 4-Amino-5-oxoproline methyl ester; 89971-20-0; Methyl 4-aminolevulinate proline analog
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Oxo-Proline Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the stringent requirements of research and cGMP manufacturing environments. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.