Description

Cholecystokinin n-Acetyl Fragment 26-30 Amide,Non-Sulfated is a synthetic peptide fragment derived from the C-terminal region of the cholecystokinin (CCK) hormone. This non-sulfated analog is a critical research tool for studying the structure-activity relationships and receptor binding mechanisms of CCK without the sulfation-dependent activity profile. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on neurobiology, gastroenterology, and peptide-based drug discovery.

Application

• Neuroscientific Research: Used as a reference standard and active agent in studies investigating CCK's role in satiety, anxiety, pain modulation, and memory processes.
• Receptor Binding Assays: Serves as a key ligand for characterizing and mapping CCK receptor subtypes (CCKA and CCKB/gastrin receptors) due to its defined structure.
• Pharmaceutical Development: Acts as a precursor or intermediate in the synthesis and screening of novel peptide therapeutics targeting metabolic and central nervous system disorders.
• Biochemical Tool: Employed in enzyme studies and as a control in analytical method development (HPLC, MS) for peptide quantification and purity assessment.
• Academic & Clinical Studies: Facilitates fundamental research into gastrointestinal physiology and the development of diagnostic probes.

Basic Information

Product Name	Cholecystokinin n-Acetyl Fragment 26-30 Amide,Non-Sulfated
CAS No.	89911-72-8
Molecular Formula	C34H56N10O9
Molecular Weight	748.88 g/mol
Synonyms	CCK Fragment 26-30 Amide, Non-Sulfated; Ac-CCK-26-30-NH2; Cholecystokinin (26-30), N-acetyl-, amide; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 fragment (non-sulfated analog); CCK-8 (26-30) fragment amide; Ac-Asp-Tyr-Met-Gly-Trp-NH2; CCK-5 amide, non-sulfated; Peptide CCK (26-30)
EINECS	Contact for details

Quality Control

Every batch of our Cholecystokinin n-Acetyl Fragment 26-30 Amide,Non-Sulfated is manufactured and analyzed under strict quality management protocols. We guarantee high purity standards suitable for advanced research applications. Comprehensive analytical data, including HPLC purity, MS confirmation, and amino acid analysis, are documented in the batch-specific Certificate of Analysis (COA), which is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.