Description

5,5,5-Trifluoropentanonitrile is a versatile fluorinated nitrile building block, valued for its unique trifluoromethyl group which imparts enhanced lipophilicity and metabolic stability to target molecules. This compound is essential for the synthesis of advanced agrochemicals, pharmaceuticals, and specialty materials. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for constructing complex fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing their dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine functionality into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., nucleophilic addition, cyclization) to create complex fluoroorganic compounds for research and scale-up.

Basic Information

Product Name	5,5,5-Trifluoropentanonitrile
CAS No.	89866-61-5
Molecular Formula	C5H6F3N
Molecular Weight	137.10 g/mol
Synonyms	5,5,5-Trifluorovaleronitrile; 5,5,5-Trifluoropentanenitrile; 4-Trifluoromethylbutyronitrile; Pentanenitrile, 5,5,5-trifluoro-; 5,5,5-Trifluoro-1-cyanobutane
EINECS	Contact for details

Quality Control

Our 5,5,5-Trifluoropentanonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. This material is moisture-sensitive; keep container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.