Description

Interferon, Alpha 1(111-166) is a defined peptide fragment derived from the human interferon α-1 protein, with the CAS registry number 89789-11-7. This high-purity synthetic peptide is critical for advanced biochemical research and pharmaceutical development, offering a precise tool for studying interferon signaling pathways and receptor interactions. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on immunology, antiviral therapies, and cytokine research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of interferon alpha receptor (IFNAR) binding, signaling cascades, and immunomodulatory effects.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the R&D of novel biologic therapeutics, including interferon-based drugs and peptide conjugates.
• Diagnostic Reagent Production: Employed in the development and calibration of immunoassays (e.g., ELISA) and other diagnostic kits designed to detect interferon activity or antibodies.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate its effects on cell proliferation, antiviral states, and major histocompatibility complex (MHC) expression.
• Structure-Activity Relationship (SAR) Studies: Provides a well-characterized fragment for mapping the functional domains of interferon alpha and designing novel peptide analogs.

Basic Information

Product Name	Interferon, Alpha 1(111-166)
CAS No.	89789-11-7
Molecular Formula	C273H432N78O81S5
Molecular Weight	~6290.0 g/mol (monoisotopic)
Synonyms	IFN-α1 (111-166); Interferon α-1 fragment 111-166; Hu-IFN-alpha1(111-166); LeIF I; Interferon, leukocyte (human clone pIF-2 protein moiety reduced); Synthetic interferon alpha peptide; IFN alpha 1 C-terminal fragment; Recombinant Interferon α-1 (111-166) peptide
EINECS	Contact for details

Quality Control

Our Interferon, Alpha 1(111-166) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to a comprehensive suite of analytical tests, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to guarantee compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.