Description

(R)-n-Boc-2-(7'-Octenyl)Glycine is a high-purity, non-natural amino acid derivative featuring a chiral center and a terminal olefin handle. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling the introduction of unique structural and functional properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of novel therapeutics and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used to incorporate constrained, hydrophobic amino acid analogs into peptide sequences to modulate bioavailability, potency, and metabolic stability.
• Chemical Biology: Serves as a versatile building block for synthesizing probes, inhibitors, and labeled peptides for studying biological pathways and protein-protein interactions.
• Peptidomimetic Design: Essential for creating peptide mimics where the olefin side chain can be further functionalized via click chemistry or other cross-coupling reactions.
• Asymmetric Synthesis: Employed as a starting material or intermediate in sophisticated multi-step organic syntheses requiring high enantiomeric purity.

Basic Information

Product Name	(R)-n-Boc-2-(7'-Octenyl)Glycine
CAS No.	89760-47-4
Molecular Formula	C₁₅H₂₇NO₄
Molecular Weight	285.38 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)dec-9-enoic acid; (R)-Boc-2-(7-Octenyl)glycine; (R)-N-Boc-2-(7'-Octenyl)glycine; (R)-2-(Boc-amino)dec-9-enoic acid; Boc-(R)-2-(7-Octenyl)Gly-OH; (R)-2-Amino-2-(7-octenyl)acetic acid tert-butyl ester; tert-Butyl (R)-2-amino-2-(7-octenyl)acetate
EINECS	Contact for details

Quality Control

Our (R)-n-Boc-2-(7'-Octenyl)Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and standard purity assays. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications for identity, purity, and related substances to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.