Description

[Ala19]Glucagon-Like Peptide II, Rat is a synthetic, bioactive peptide analog of glucagon-like peptide 2 (GLP-2). This compound is of significant value for research into intestinal growth, nutrient absorption, and gastrointestinal tract repair mechanisms. It serves as a critical tool for pharmaceutical R&D, academic research, and biotechnology applications focused on metabolic and digestive system disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological roles of GLP-2.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for developing novel therapeutics targeting short bowel syndrome, Crohn's disease, and other intestinal disorders.
• Mechanistic Studies: Employed in in vitro and in vivo models to elucidate signaling pathways related to intestinal epithelial cell proliferation and survival.
• Receptor Binding Assays: Utilized in competitive binding studies to characterize and validate GLP-2 receptor (GLP-2R) interactions and affinity.
• Academic & Institutional Research: A key reagent for universities and research institutes exploring endocrinology, gastroenterology, and peptide hormone action.

Basic Information

Product Name	[Ala19]Glucagon-Like Peptide II, Rat
CAS No.	89750-15-2
Molecular Formula	C149H246N44O48
Molecular Weight	~3350.9 g/mol
Synonyms	[Ala19]GLP-2, Rat; Ala19-GLP-2 (rat); Rat [Ala19]GLP-2; Glucagon-like peptide 2 (1-34), rat, Ala19-; H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Lea-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH; GLP-2 (rat) analog; GLP-2 fragment (1-34), rat, [Ala19]-
EINECS	Contact for details

Quality Control

Our [Ala19]Glucagon-Like Peptide II, Rat is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including reversed-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This hygroscopic and light-sensitive material should be allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.