Description

1H-Imidazole-4-Carboxylicacid,2,5-Difluoro-(9Ci) is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. Its primary utility lies in the synthesis of complex molecules for the pharmaceutical, agrochemical, and specialty chemical industries, enabling the creation of next-generation products with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides, where the difluoroimidazole moiety contributes to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the synthesis of specialty polymers, organic electronic materials, and metal-organic frameworks (MOFs) due to its rigid, functionalized heterocyclic structure.
• Chemical Biology Probes: Utilized in the development of fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.

Basic Information

Product Name	1H-Imidazole-4-Carboxylicacid,2,5-Difluoro-(9Ci)
CAS No.	89676-60-8
Molecular Formula	C4H2F2N2O2
Molecular Weight	148.07 g/mol
Synonyms	2,5-Difluoro-1H-imidazole-4-carboxylic acid; 2,5-Difluoro-4-imidazolecarboxylic acid; 2,5-Difluoroimidazole-4-carboxylic acid; 4-Carboxy-2,5-difluoroimidazole; 1H-Imidazole-4-carboxylic acid, 2,5-difluoro-; 89676-60-8
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carboxylicacid,2,5-Difluoro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with every batch, detailing all relevant specifications to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.