Description

R-Cefotetan is a semi-synthetic, broad-spectrum cephamycin antibiotic belonging to the second-generation cephalosporin class. Its primary value lies in its potent activity against a wide range of Gram-negative and anaerobic bacteria, including many β-lactamase-producing strains. This makes it a critical intermediate and active pharmaceutical ingredient (API) for the development of injectable antibiotic formulations. Key industries that rely on this compound include pharmaceutical manufacturing, research and development for new antimicrobial agents, and reference standard production for quality control laboratories.

Application

• Pharmaceutical API Synthesis: Serves as the core active ingredient in the manufacture of sterile injectable antibiotic drugs.
• Research & Development: Used in preclinical and clinical studies for developing new antibacterial therapies and combination drugs.
• Reference Standard: Employed as a high-purity chemical standard in analytical laboratories for HPLC, LC-MS, and microbiological assay calibration.
• Antimicrobial Susceptibility Testing: Utilized in preparing discs or solutions for in-vitro testing to determine bacterial resistance profiles.
• Veterinary Medicine: Potential application in developing antibacterial treatments for veterinary use.

Basic Information

Item	Details
Product Name	R-Cefotetan
CAS No.	89495-45-4
Molecular Formula	C₁₇H₁₇N₇O₈S₄
Molecular Weight	575.62 g/mol
Synonyms	Cefotetan; (6R,7R)-7-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-Methoxycephem; Cefotetan Acid; Apatef; Yamatetan; Cefotan; Antibiotic YM 09330
EINECS	Contact for details

Quality Control

Our R-Cefotetan CAS NO 89495-45-4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identification by IR and NMR spectroscopy, and tests for related substances and residual solvents to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) documenting identity, purity, and safety parameters is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.