Description

(Tyr52)-Pth (52-84) (Human) is a synthetic peptide fragment corresponding to a specific region of the human parathyroid hormone (PTH). This high-purity reference standard is critical for advanced biochemical research and assay development, offering researchers a precise tool for studying PTH structure, function, and receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on metabolic bone disorders, calcium homeostasis, and endocrine system research.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of parathyroid hormone structure-activity relationships and receptor binding mechanisms.
• Assay Development & Calibration: Serves as a critical calibrant and control material in the development and validation of immunoassays (e.g., ELISA, RIA) for PTH detection.
• Pharmaceutical R&D: Employed in drug discovery programs targeting PTH receptors for the treatment of osteoporosis and other bone metabolism disorders.
• Academic Studies: A key reagent for investigating calcium and phosphate regulation, endocrine signaling pathways, and related metabolic processes.
• Quality Control: Used as a system suitability standard in analytical laboratories to ensure the performance of chromatographic (HPLC) and mass spectrometric methods for peptide analysis.

Basic Information

Product Name	(Tyr52)-Pth (52-84) (Human)
CAS No.	89492-47-7
Molecular Formula	C164H256N46O48S
Molecular Weight	3707.2 g/mol
Synonyms	Parathyroid Hormone (52-84), human, Tyr52-substituted; PTH (52-84), human; hPTH(52-84); Parathyrin (52-84); Tyr52-PTH(52-84); [Tyr52]Parathyroid Hormone (52-84); [Tyr52]hPTH(52-84); Parathyroid hormone fragment 52-84
EINECS	Contact for details

Quality Control

Every batch of (Tyr52)-Pth (52-84) (Human) is manufactured and tested under stringent quality management systems. Our products undergo rigorous analytical testing, including reverse-phase HPLC and mass spectrometry, to ensure high purity and precise molecular identity. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. Solutions should be prepared fresh or aliquoted and stored at ≤ -20°C for short-term use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.