Description

T-Butoxyacetylene is a highly versatile and reactive terminal alkyne derivative, serving as a crucial building block in advanced organic synthesis. Its core value lies in its ability to act as a protected acetylene equivalent, enabling the controlled introduction of acetylene units into complex molecules under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, facilitating the synthesis of active ingredients, fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the construction of heterocyclic compounds and complex molecular scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkyne functionalities.
• Material Science: Employed in the development of specialty polymers, dendrimers, and advanced organic electronic materials via click chemistry and other coupling reactions.
• Fine Chemical Production: Serves as a precursor for vitamins, flavors, fragrances, and other high-value specialty chemicals.
• Cross-Coupling Reactions: An effective reagent in Sonogashira, Glaser, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Protecting Group Strategy: The tert-butoxy group acts as a protective moiety for the acetylene, which can be selectively deprotected to reveal the free alkyne for subsequent reactions.

Basic Information

Product Name	T-Butoxyacetylene
CAS No.	89489-28-1
Molecular Formula	C6H10O
Molecular Weight	98.14 g/mol
Synonyms	tert-Butoxyacetylene; 3,3-Dimethyl-1-butyn-1-ol tert-Butyl Ether; 1-tert-Butoxy-1-butyne; 1-(tert-Butoxy)ethyne; Ethynyl tert-butyl ether; tert-Butyl ethynyl ether
EINECS	Contact for details

Quality Control

Our T-Butoxyacetylene is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at temperatures between 2°C and 8°C. Keep away from heat, sparks, and open flames. Containers should be kept tightly sealed when not in use to prevent evaporation and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.