Description

β-Dihydroaldosterone-γ-Etiolactone is a high-purity steroidal intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in the field of endocrinology. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the exploration of new drug candidates targeting hormone receptors and metabolic pathways.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating aldosterone metabolism, steroidogenesis, and related enzymatic processes.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized steroidal compounds.

Basic Information

Product Name	β-Dihydroaldosterone-γ-Etiolactone
CAS No.	89327-73-1
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	18,11β-Hemiacetal of 3β,21-Dihydroxy-5β-pregnane-11,18-dione, 18→11β-Lactone; 3β,21-Dihydroxy-5β-pregnane-11,18-dione 18,11β-Hemiacetal 18→11β-Lactone; 11β,18-Epoxy-3β,21-dihydroxy-5β-pregnan-20-one; Dihydroaldosterone γ-Lactone; Aldosterone Dihydro Derivative Lactone
EINECS	Contact for details

Quality Control

Our β-Dihydroaldosterone-γ-Etiolactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.