Description

Thiophosphoenolpyruvate is a high-purity, specialized biochemical reagent with the CAS number 89232-34-8. This compound serves as a critical thiophosphate analog of phosphoenolpyruvate, enabling advanced research in enzymatic mechanisms and metabolic pathway studies. It is essential for pharmaceutical R&D, academic biochemistry laboratories, and biotechnology companies focused on enzyme inhibition, metabolic engineering, and the development of novel biochemical probes.

Application

• Enzymology Research: Used as a substrate analog to study the kinetics and mechanisms of pyruvate kinase and other phosphoenolpyruvate-utilizing enzymes.
• Metabolic Pathway Analysis: A key tool for investigating sulfur incorporation and thiophosphate transfer in biochemical networks.
• Pharmaceutical Development: Serves as a building block or intermediate in the research and synthesis of novel therapeutic agents targeting metabolic diseases.
• Biochemical Probe Synthesis: Utilized in the creation of labeled or modified compounds for tracing metabolic fluxes and protein interactions.
• Academic & Industrial R&D: Fundamental reagent for universities and biotech firms conducting cutting-edge research in biochemistry and molecular biology.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic kits and assay components.

Basic Information

Product Name	Thiophosphoenolpyruvate
CAS No.	89232-34-8
Molecular Formula	C3H5O6PS
Molecular Weight	200.11 g/mol
Synonyms	Phosphoenolpyruvic Acid Thio Analog; PEP Thioanalog; (Z)-3-Phosphonooxy-2-(thiophosphonooxy)acrylic Acid; Thiophospho(enol)pyruvic Acid; 2-(Phosphonatooxy)-3-(thiophosphonatooxy)prop-2-enoic Acid; TEP; Thiophosphoenol Pyruvate
EINECS	Contact for details

Quality Control

Our Thiophosphoenolpyruvate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere or with desiccant after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by titration)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.