Description

2,3,4-Tri-o-Acetyl-D-Arabinopyranosyl Cyanide is a key acetylated glycosyl cyanide building block used in synthetic organic chemistry. This compound is valued for its role as a versatile glycosyl donor in the stereoselective synthesis of nucleoside analogs and complex carbohydrate derivatives. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and other bioactive molecules.

Application

• Nucleoside Analog Synthesis: Serves as a critical glycosyl donor for constructing the sugar moiety in modified nucleosides with potential antiviral or anticancer activity.
• Carbohydrate Chemistry: Used in the stereocontrolled synthesis of oligosaccharides, glycoconjugates, and other complex sugar derivatives for biological studies.
• Pharmaceutical Intermediates: Acts as a high-value chiral intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Glycosylation Reactions: Employed in Lewis acid-catalyzed glycosylation to introduce the arabinopyranosyl unit into various aglycone acceptors.
• Chemical Biology Probes: Useful for creating labeled carbohydrate probes to study glycosylation processes and enzyme mechanisms.
• Process Development & Scale-up: Supplied for route scouting and optimization in medicinal chemistry and kilo-lab scale production.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-D-Arabinopyranosyl Cyanide
CAS No.	89158-08-7
Molecular Formula	C12H15NO7
Molecular Weight	285.25 g/mol
Synonyms	2,3,4-Tri-O-acetyl-α-D-arabinopyranosyl cyanide; 2,3,4-Tri-O-acetyl-α-D-arabinopyranosyl cyanide; α-D-Arabinopyranosyl cyanide, 2,3,4-triacetate; 1-Cyano-2,3,4-tri-O-acetyl-α-D-arabinopyranose; D-Arabinopyranosyl cyanide, 2,3,4-triacetate; Triacetyl-D-arabinopyranosyl cyanide
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-D-Arabinopyranosyl Cyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.