Description

Tazobactam Acid Impurity 14 is a high-purity chemical reference standard critical for pharmaceutical research and development. This compound serves as a specified impurity in the quality control and analytical profiling of Tazobactam, a vital β-lactamase inhibitor used in combination antibiotic therapies. It is essential for analytical chemists and quality assurance professionals in the pharmaceutical industry who require precise standards for method development, validation, and regulatory compliance to ensure drug safety and efficacy.

Application

• Primary use as a certified reference standard for the identification and quantification of impurities in Tazobactam Active Pharmaceutical Ingredient (API).
• Critical component in analytical method development and validation (HPLC, UPLC, LC-MS) for pharmaceutical quality control laboratories.
• Used in stability studies and forced degradation studies to understand the degradation pathways of Tazobactam.
• Essential for regulatory filing and compliance (e.g., ICH guidelines, FDA, EMA) requiring impurity characterization.
• Supports research and development of new synthetic routes and purification processes for Tazobactam.
• Utilized by contract research organizations (CROs) and testing laboratories offering analytical services to the pharma sector.

Basic Information

Product Name	Tazobactam Acid Impurity 14
CAS No.	89051-49-0
Molecular Formula	C10H11N5O5S
Molecular Weight	313.29 g/mol
Synonyms	(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; Tazobactam Impurity 14; Tazobactam Related Compound 14; TAZ Impurity 14; 3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; Tazobactam Acidic Impurity; Tazobactam Degradant
EINECS	Contact for details

Quality Control

Every batch of Tazobactam Acid Impurity 14 is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic techniques, to ensure compliance with industry standards for reference materials. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profile. We support compliance with ICH Q3A/B guidelines and other relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 1.0% Total impurities: ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.