Description

Deaminoethyl Fluvoxamine β-D-Glucuronide is a high-purity reference standard and pharmaceutical intermediate of significant analytical and synthetic importance. This compound is critical for research and development in the pharmaceutical industry, particularly for method validation, pharmacokinetic studies, and quality control of related active pharmaceutical ingredients (APIs). It is primarily required by analytical laboratories, research institutions, and manufacturers engaged in the development and production of neuropsychiatric therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of Fluvoxamine and its metabolites via HPLC, LC-MS, or GC-MS.
• Metabolite Research: Essential for studying the pharmacokinetics, metabolic pathways, and bioavailability of Fluvoxamine in preclinical and clinical research.
• Impurity Profiling: Serves as a known impurity or degradation product standard to monitor and control the quality of Fluvoxamine maleate API during manufacturing and stability testing.
• Bioanalytical Assay Development: Employed in the development and validation of robust bioanalytical methods for therapeutic drug monitoring (TDM) and forensic toxicology.
• Chemical Synthesis Intermediate: Utilized as a key building block in the organic synthesis of novel chemical entities or labeled analogs for tracer studies.

Basic Information

Product Name	Deaminoethyl Fluvoxamine β-D-Glucuronide
CAS No.	89035-93-8
Molecular Formula	C23H28F2N2O8
Molecular Weight	498.47 g/mol
Synonyms	Fluvoxamine N-β-D-Glucuronide (Deaminoethyl); 5-Methoxy-4'-(trifluoromethyl)valerophenone O-β-D-Glucuronide (related); Fluvoxamine Metabolite Glucuronide; 1-[2-(Aminomethyl)-4-(3,4-difluorophenoxy)butyl]-4-(trifluoromethyl)benzene β-D-Glucopyranosiduronic Acid (Deamino); Deamino-Fluvoxamine Glucuronide
EINECS	Contact for details

Quality Control

Our Deaminoethyl Fluvoxamine β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity (HPLC), structural confirmation (NMR, MS), and residual solvent analysis to ensure it meets the stringent requirements for use as a reference standard. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions upon opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.