Description

3-(2,2,2-Trifluoroacetamido)Benzeneboronic Acid is a high-purity, specialty boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a trifluoroacetamido-protected aniline moiety, enabling precise cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the boronic acid group for efficient carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the synthesis of activity-based probes for protein labeling and study.
• Process Chemistry & Scale-up: Provides a reliable and consistent building block for the optimization and commercial-scale production of fine chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	3-(2,2,2-Trifluoroacetamido)Benzeneboronic Acid
CAS No.	88978-20-5
Molecular Formula	C8H7BF3NO3
Molecular Weight	233.96 g/mol
Synonyms	3-(Trifluoroacetamido)benzeneboronic Acid; [3-(2,2,2-Trifluoroacetamido)phenyl]boronic Acid; 3-Aminophenylboronic Acid Trifluoroacetamide; N-[3-(Boronophenyl)]-2,2,2-trifluoroacetamide; 3-(Trifluoroacetylamino)phenylboronic Acid; 3-TFA-APBA; 3-Carboxamido, N-trifluoroacetyl, Benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(2,2,2-Trifluoroacetamido)Benzeneboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.