Description

1-(Benzyloxy)-4-(Difluoromethoxy)Benzene is a high-purity aromatic ether compound featuring both benzyloxy and difluoromethoxy functional groups. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for specialty chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial building block for developing advanced pesticides and herbicides, where the difluoromethoxy group can improve biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protected phenol derivative in multi-step synthetic routes in fine chemical production.

Basic Information

Product Name	1-(Benzyloxy)-4-(Difluoromethoxy)Benzene
CAS No.	88798-08-7
Molecular Formula	C14H12F2O2
Molecular Weight	250.24 g/mol
Synonyms	4-(Benzyloxy)-1-(difluoromethoxy)benzene; p-(Benzyloxy)phenyl difluoromethyl ether; Benzyl 4-(difluoromethoxy)phenyl ether; 1-(Difluoromethoxy)-4-(phenylmethoxy)benzene; 4-(Difluoromethoxy)phenyl benzyl ether; α-(4-(Difluoromethoxy)phenoxy)toluene
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-4-(Difluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for cGMP and ISO guided applications in pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.