Description

Preclamol Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in neuropharmacology. Its value lies in its role as a key building block for the synthesis of novel dopaminergic agents and as a reference standard in analytical research. This compound is essential for pharmaceutical R&D laboratories, academic institutions, and manufacturers focused on developing treatments for central nervous system disorders.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of advanced dopaminergic compounds and potential therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Serves as a tool compound in neuroscience research to study dopamine receptor pharmacology and signaling pathways.
• Active Pharmaceutical Ingredient (API) Development: Employed in the early-stage development and scale-up of new chemical entities (NCEs).
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for pharmacological studies.

Basic Information

Product Name	Preclamol Hydrochloride
CAS No.	88768-67-6
Molecular Formula	C17H25NO2 • HCl
Molecular Weight	311.85 g/mol (Free base: 275.39 g/mol)
Synonyms	(-)-3-PPP Hydrochloride; (-)-3-(3-Hydroxyphenyl)-N-propylpiperidine Hydrochloride; Preclamol HCl; PD-128,907 (Hydrochloride); (3R)-3-(3-Hydroxyphenyl)-1-propylpiperidine Hydrochloride; (-)-3-(3-Hydroxyphenyl)-N-n-propylpiperidine Hydrochloride
EINECS	Contact for details

Quality Control

Our Preclamol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.