Description

Methyl 2-Amino-3-Methoxypropanoate Hydrochloride is a high-purity, protected amino acid ester hydrochloride salt, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a reactive amine group in a stable, crystalline form, essential for constructing complex molecular architectures with precise stereochemistry. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the production of active pharmaceutical ingredients (APIs), peptides, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Protease Inhibitor Development: Serves as a core structural component for designing enzyme inhibitors.
• Agrochemical Synthesis: Employed in the research and development of advanced, chiral pesticides and herbicides.
• Ligand and Catalyst Preparation: Useful for creating chiral ligands for asymmetric catalysis.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Methyl 2-Amino-3-Methoxypropanoate Hydrochloride
CAS No.	88642-83-5
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	Methyl 3-Methoxy-2-aminopropanoate hydrochloride; 2-Amino-3-methoxypropionic acid methyl ester hydrochloride; L-2-Amino-3-methoxypropionic acid methyl ester hydrochloride (if applicable); Methyl β-methoxyalaninate hydrochloride; Alanine, 3-methoxy-, methyl ester, hydrochloride; Methyl O-methyl-DL-serinate hydrochloride; (RS)-Methyl 2-amino-3-methoxypropionate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Methoxypropanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.