Description

Fmoc-11-Aminoundecanoic Acid CAS NO 88574-07-6 is a high-purity, protected amino acid derivative featuring an extended 11-carbon aliphatic linker. This compound is essential for the solid-phase peptide synthesis (SPPS) of peptides requiring long, flexible, and hydrophobic spacers. It is primarily utilized by research institutions and pharmaceutical companies developing novel peptide-based therapeutics, diagnostics, and bioconjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for introducing a long-chain amino acid moiety with an Fmoc-protected α-amino group.
• Linker Chemistry: The extended hydrocarbon chain serves as an ideal spacer for attaching peptides to surfaces, carriers, or other molecules in bioconjugation and material science applications.
• Drug Discovery & Development: Used in the research and development of peptide drugs where lipophilicity and chain length are critical for bioactivity and pharmacokinetics.
• Biomaterial Functionalization: Employed to create peptide-modified surfaces for tissue engineering, biosensors, and diagnostic assays.
• Antibody-Drug Conjugate (ADC) Payloads: Can be incorporated into the design of linker-payload systems for targeted cancer therapies.
• Custom Peptide Services: A critical reagent for CROs and CDMOs offering bespoke peptide synthesis to client specifications.

Basic Information

Product Name	Fmoc-11-Aminoundecanoic Acid
CAS No.	88574-07-6
Molecular Formula	C26H33NO4
Molecular Weight	423.55 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-11-aminoundecanoic acid; Fmoc-11-AUA-OH; Fmoc-NH-(CH2)10-COOH; 11-[(9-Fluorenylmethyloxycarbonyl)amino]undecanoic acid; N-Fmoc-11-aminoundecanoic acid; Fmoc-11-amino-undecanoic acid; N-α-Fmoc-11-aminoundecanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-11-Aminoundecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced peptide synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.