Description

(4-Fluoronaphthalen-1-Yl)Methanamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive primary amine group and a fluorinated naphthalene scaffold, enabling the construction of complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, due to the lipophilicity and potential metabolic stability imparted by the fluoronaphthalene moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis, leveraging the amine functionality for coordination or activation.
• Material Science Precursor: Acts as a monomer or functionalization agent in the production of advanced polymers, dyes, and liquid crystals, where the fluorinated aromatic system modifies optical and electronic properties.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination effects, reaction mechanisms, and structure-activity relationships (SAR) in medicinal and synthetic chemistry.

Basic Information

Product Name	(4-Fluoronaphthalen-1-Yl)Methanamine
CAS No.	88536-35-0
Molecular Formula	C₁₁H₁₀FN
Molecular Weight	175.20 g/mol
Synonyms	1-(Aminomethyl)-4-fluoronaphthalene; 4-Fluoro-1-naphthalenemethylamine; 1-(Aminomethyl)-4-fluoronaphthalene; 4-Fluoronaphthalen-1-ylmethanamine; (4-Fluoro-1-naphthyl)methanamine; 4-Fluoro-1-naphthalenemethanamine; 1-Fluoro-4-(aminomethyl)naphthalene
EINECS	Contact for details

Quality Control

Our (4-Fluoronaphthalen-1-Yl)Methanamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.