Description

1-Boc-3-Carbamoyl Piperidine is a high-purity, protected piperidine derivative widely used as a critical building block in organic synthesis. This compound is essential for the development of novel pharmaceutical agents, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of piperidine-based active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Peptidomimetic Synthesis: Used in the design and synthesis of peptide analogs and mimetics due to its protected amine and amide functionalities.
• Agrochemical Development: Employed as an intermediate in the research and production of advanced crop protection chemicals.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis services targeting specialized molecular targets.

Basic Information

Product Name	1-Boc-3-Carbamoyl Piperidine
CAS No.	88466-77-7
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide; 3-Carbamoylpiperidine-1-carboxylic Acid tert-Butyl Ester; tert-Butyl 3-carbamoylpiperidine-1-carboxylate; N-Boc-3-piperidinecarboxamide; 1-N-Boc-3-aminocarbonylpiperidine; 1-Boc-piperidine-3-carboxamide; Piperidine-3-carboxamide, 1-(1,1-dimethylethoxy)carbonyl]-; 1-Boc-3-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Carbamoyl Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.