Description

Buparvaquone is a synthetic hydroxynaphthoquinone compound with potent antiprotozoal activity. It is a critical active pharmaceutical ingredient (API) primarily valued for its efficacy against specific parasitic infections in veterinary medicine. This high-purity compound is essential for manufacturers developing pharmaceutical formulations for the animal health industry, particularly for the treatment of theileriosis.

Application

• Veterinary Pharmaceutical API: Primary use as the active ingredient in injectable solutions for the treatment of bovine theileriosis (East Coast fever) caused by *Theileria parva*.
• Animal Health Formulations: Used in the development and production of intramuscular or subcutaneous injectable formulations for cattle.
• Parasiticide Research: Serves as a reference standard and key intermediate in antiprotozoal drug discovery and development programs.
• Veterinary Generic Drug Manufacturing: A crucial component for companies producing generic versions of established theileriosis treatments.

Basic Information

Product Name	Buparvaquone
CAS No.	88426-33-9
Molecular Formula	C₂₁H₂₈O₃
Molecular Weight	328.45 g/mol
Synonyms	2-[(4-tert-Butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone; BW 993C; Butalex; 1,4-Naphthalenedione, 2-[[(1,1-dimethylethyl)cyclohexyl]methyl]-3-hydroxy-; 2-[(trans-4-tert-Butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone; Vetbutalex; Hydroxynaphthoquinone BW 993C
EINECS	Contact for details

Quality Control

Our Buparvaquone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by IR spectroscopy, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with cGMP guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.