Description

Amprolium CAS NO 121-25-5 is a synthetic thiamine analogue primarily used as a coccidiostat in veterinary medicine. This compound is critical for the prevention and control of coccidiosis, a parasitic disease that causes significant economic losses in poultry and livestock production. It is an essential active pharmaceutical ingredient (API) for manufacturers of veterinary premixes, feed additives, and pharmaceutical formulations targeting the poultry, cattle, and sheep industries.

Application

• Veterinary Feed Additives: Primary use as a coccidiostat in medicated feeds for broilers, layers, and turkeys.
• Veterinary Pharmaceutical Formulations: Key API in oral solutions, powders, and tablets for the treatment and prevention of coccidiosis.
• Livestock Health: Used in feed for calves, lambs, and other ruminants to control coccidial infections.
• Premix Manufacturing: Supplied as a high-purity raw material for the production of concentrated nutritional and medicinal premixes.
• Aquaculture: Investigational and potential application in controlling related protozoan parasites in farmed fish.
• Research & Development: Used in biochemical and pharmacological studies as a thiamine antagonist.

Basic Information

Product Name	Amprolium
CAS No.	121-25-5
Molecular Formula	C14H19ClN4
Molecular Weight	278.78 g/mol
Synonyms	1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride; Amprol; Amprolium hydrochloride; Corid; Coxistac; Pancoxin; Amprolium chloride; 2-Methyl-4-amino-5-[(2-methyl-1H-imidazol-1-yl)methyl]pyrimidine (base structure reference)
EINECS	204-459-2

Quality Control

Our Amprolium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for veterinary pharmaceutical applications. Comprehensive testing includes identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting compliance with in-house specifications is provided with every shipment. We can support compliance with relevant pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.