Description

Benznidazole CAS NO 22994-85-0 is a nitroimidazole derivative and a critical antiparasitic agent. It is an essential pharmaceutical active ingredient for the treatment of Chagas disease (American trypanosomiasis). This compound is primarily required by the pharmaceutical industry for the formulation of antiprotozoal medications and for research into novel therapeutic applications.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of antiparasitic drugs targeting Trypanosoma cruzi.
• Key component in the formulation of tablets and other oral dosage forms for the treatment of Chagas disease.
• Reference standard in analytical laboratories for quality control and method development.
• Critical raw material for research and development of new antiparasitic agents and combination therapies.
• Used in preclinical and clinical studies to evaluate efficacy and pharmacokinetics.
• Essential for global health programs and initiatives aimed at eliminating neglected tropical diseases.

Basic Information

Product Name	Benznidazole
CAS No.	22994-85-0
Molecular Formula	C12H12N4O3
Molecular Weight	260.25 g/mol
Synonyms	N-Benzyl-2-nitro-1-imidazoleacetamide; Radanil; Rochagan; Ro 7-1051; Benznidazol; N-Benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide; 1-[(2-Nitro-1-imidazolyl)acetyl]-2-benzylamine
EINECS	Contact for details

Quality Control

Our Benznidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.