Description

Pentamidine is a potent aromatic diamidine compound with significant therapeutic and research applications. This compound is valued for its antiprotozoal and antimicrobial properties, making it a critical active pharmaceutical ingredient (API). It is primarily utilized by the pharmaceutical industry for the formulation of injectable medications and serves as a key intermediate in advanced chemical synthesis. Our supply of Pentamidine CAS NO 100-33-4 ensures high purity and reliable consistency for demanding industrial and research needs.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable treatments for specific parasitic infections, such as Pneumocystis pneumonia (PCP) and certain forms of leishmaniasis.
• Research Chemical: Utilized in biochemical and pharmacological research to study its mechanism of action against protozoa and fungi.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for drug testing and method validation.
• Chemical Synthesis: Acts as a crucial building block or intermediate in the synthesis of more complex diamidine derivatives and related bioactive compounds.

Basic Information

Product Name	Pentamidine
CAS No.	100-33-4
Molecular Formula	C19H24N4O2
Molecular Weight	340.42 g/mol
Synonyms	Pentamidine Isethionate (salt form); 4,4'-[Pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide; 1,5-Bis(4-amidinophenoxy)pentane; Lomidine; Nebupent; Pentacarinat; Diamidine
EINECS	202-839-0

Quality Control

Our Pentamidine is manufactured under strict quality management systems to meet the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.