Description

Misonidazole CAS NO 13551-87-6 is a nitroimidazole derivative that functions as a potent radiosensitizer for hypoxic tumor cells. This compound is critical in pre-clinical oncology research for studying the enhancement of radiation therapy efficacy. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals for investigative and development purposes.

Application

• Pre-clinical Radiosensitizer Research: Used in laboratory studies to investigate the potentiation of radiation effects on hypoxic cancer cells.
• Oncology Drug Development: Serves as a key reference compound and intermediate in the development of novel anti-cancer therapeutics.
• Biochemical Mechanism Studies: Employed to study the biochemical pathways of nitroreductase enzymes and hypoxia-selective cytotoxicity.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the synthesis of more complex nitroimidazole-based molecules.

Basic Information

Product Name	Misonidazole
CAS No.	13551-87-6
Molecular Formula	C₇H₁₁N₃O₄
Molecular Weight	201.18 g/mol
Synonyms	1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol; Ro-07-0582; NSC 261036; MISO; α-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol; 2-Nitro-1-(3-methoxy-2-hydroxypropyl)imidazole
EINECS	Contact for details

Quality Control

Our Misonidazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.