Description

Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Bis(Trifluoromethyl)-, Ethyl Ester is a highly fluorinated cyclopropane derivative valued for its unique structural and electronic properties. This compound serves as a critical advanced intermediate in the synthesis of complex molecules, particularly in high-value sectors. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical industries for research and development, as well as process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluoro- and trifluoromethyl groups impart specific biological activity and environmental persistence profiles.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric materials due to its influence on polarity and molecular alignment.
• Polymer & Material Science: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy properties.
• Organic Synthesis & Catalysis: A versatile reagent in organofluorine chemistry for constructing complex, fluorinated ring systems and as a ligand precursor in catalysis.
• Research & Development: Essential for academic and industrial R&D exploring new reactions, material properties, and structure-activity relationships in fluoroorganic chemistry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Bis(Trifluoromethyl)-, Ethyl Ester
CAS No.	88382-41-6
Molecular Formula	C9H6F8O2
Molecular Weight	298.13 g/mol
Synonyms	Ethyl 2,2-Difluoro-3,3-bis(trifluoromethyl)cyclopropanecarboxylate; 2,2-Difluoro-3,3-bis(trifluoromethyl)cyclopropanecarboxylic Acid Ethyl Ester; 1,1'-(2,2-Difluoro-1,3-propanediyl)bis(1,1,2,2,2-pentafluoroethyl) Ethyl Ester (alternative); Difluorobis(trifluoromethyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl 2,2-Difluoro-3,3-bis(trifluoromethyl)cyclopropane-1-carboxylate; FCO-187; FC-187 (potential trade/abbreviation).
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Bis(Trifluoromethyl)-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical specifications to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its sensitivity to strong bases and fluorides, ensure segregation from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.