Description

3-Bromo-1,1,1-Trifluoro-2-Propanol is a versatile fluorinated organic building block, prized for its unique combination of bromine and trifluoromethyl groups which impart significant reactivity and lipophilicity. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure enables the introduction of key functional motifs. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or brominated moieties to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine atoms into polymer chains, enhancing chemical resistance, lowering surface energy, and improving material properties for coatings and specialty plastics.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution, coupling reactions, and as a precursor for other fluorinated compounds like trifluoromethyl ketones and acids.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Bromo-1,1,1-Trifluoro-2-Propanol
CAS No.	88378-50-1
Molecular Formula	C3H4BrF3O
Molecular Weight	192.96 g/mol
Synonyms	2-Propanol, 3-bromo-1,1,1-trifluoro-; 3-Bromo-1,1,1-trifluoropropan-2-ol; 1,1,1-Trifluoro-3-bromo-2-propanol; 3-Bromo-1,1,1-trifluoro-isopropanol; 2-Bromo-1,1,1-trifluoroethanol (common misnomer); BTFPO; 3-Bromo-α,α,α-trifluoro-2-propanol
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,1,1-Trifluoro-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 8°C for extended stability, although the product is stable at room temperature for shorter periods. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.8 g/mL
Refractive Index (n20D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.