Description

D-Iopamidol is a high-purity, non-ionic contrast agent intermediate essential for modern diagnostic imaging. This compound is critical for ensuring the safety and efficacy of X-ray and CT scan contrast media formulations. It is primarily required by pharmaceutical manufacturers and fine chemical suppliers serving the global medical diagnostics industry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of iopamidol, a widely used non-ionic, low-osmolar contrast medium.
• Contrast Media Production: Serves as the active pharmaceutical ingredient (API) precursor for injectable solutions used in angiography, urography, and computed tomography (CT).
• Research & Development: Used in academic and industrial labs for developing new iodinated contrast agents with improved safety profiles.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a high-purity, tri-iodinated benzene derivative.

Basic Information

Product Name	D-Iopamidol
CAS No.	88375-91-1
Molecular Formula	C17H22I3N3O8
Molecular Weight	777.09 g/mol
Synonyms	Iopamidol Impurity D; (2S)-2-Hydroxy-3-[(2-hydroxy-1-oxopropyl)amino]-1-[(2,4,6-triiodo-3,5-bis[(2-hydroxy-1-oxopropyl)amino]phenyl)methyl]propyl 2-hydroxypropanoate; 5-[(2S)-2-Hydroxy-3-[(2-hydroxy-1-oxopropyl)amino]-1-[(2-hydroxy-1-oxopropoxy)methyl]propyl]carbamoyl-2,4,6-triiodobenzene-1,3-diyldiacetic acid; Iopamidol Related Compound D; Iopamidol EP Impurity D; Iopamidol USP Impurity D
EINECS	Contact for details

Quality Control

Our D-Iopamidol is manufactured under strict quality management systems. Each batch is tested to meet exacting standards for pharmaceutical intermediates, with specifications aligned to ICH guidelines and relevant pharmacopeial monographs (e.g., USP, EP). Comprehensive testing includes identity, purity, and impurity profile analysis. A Certificate of Analysis (COA) documenting all results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.