Description

β-T-Butyl-D-Alanine is a high-purity, non-natural amino acid derivative featuring a sterically hindered tert-butyl side chain. This compound is a critical chiral building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), where its structure provides enhanced metabolic stability and conformational control. It is essential for research and production in pharmaceutical development, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of protease inhibitors, antiviral drugs, and other therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce conformational constraints and improve peptide stability.
• Agrochemical Research: Serves as a building block for developing novel herbicides and pesticides with chiral specificity.
• Bioconjugation & Labeling: Utilized in the preparation of modified peptides for diagnostic assays and biochemical probes.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	β-T-Butyl-D-Alanine
CAS No.	88319-43-1
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(R)-3-Amino-3,3-dimethylbutanoic acid; D-3-Amino-3,3-dimethylbutyric acid; (R)-3-Amino-3,3-dimethylbutanoic Acid; D-tert-Butylglycine; D-Tle; D-3,3-Dimethyl-β-alanine; (R)-3,3-Dimethyl-β-alanine; D-β-tert-Butylalanine
EINECS	Contact for details

Quality Control

Our β-T-Butyl-D-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.