Description

2-Acetamido-4-Bromoanisole is a versatile brominated anisole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized aromatic scaffold with orthogonal protecting groups and reactive sites for selective cross-coupling and substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in material science for creating specialized polymers and dyes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bromine atom for further functionalization.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing brominated azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Heck, and Buchwald-Hartwig amination reactions to create biaryl structures.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and catalysis within university and industrial research laboratories.

Basic Information

Product Name	2-Acetamido-4-Bromoanisole
CAS No.	88301-40-0
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	N-(4-Bromo-2-methoxyphenyl)acetamide; 4'-Bromo-2'-methoxyacetanilide; 2-Acetamido-4-bromo-1-methoxybenzene; 1-Acetamido-2-methoxy-5-bromobenzene; 4-Bromo-2-methoxyacetanilide; Acetamide, N-(4-bromo-2-methoxyphenyl)-; 2-Methoxy-4-bromoacetanilide
EINECS	Contact for details

Quality Control

Every batch of 2-Acetamido-4-Bromoanisole is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for assay, related substances, and residual solvents is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.