Description

Phosphine, (2R,1R)-1,2-Cyclopentanediylbis[Dimethyl- (9Ci) is a specialized chiral organophosphorus compound, serving as a high-value intermediate in advanced chemical synthesis. Its precise stereochemistry makes it a critical building block for creating molecules with specific three-dimensional orientations, which is essential for developing pharmaceuticals and agrochemicals with targeted activity. This compound is primarily sought by research institutions and industrial R&D departments focused on asymmetric catalysis, ligand development, and the synthesis of novel active ingredients.

Application

• Asymmetric Catalysis: As a chiral ligand precursor or catalyst component in stereoselective organic transformations, including hydrogenation and cross-coupling reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of chiral active pharmaceutical ingredients (APIs) where specific stereochemistry is required for efficacy.
• Agrochemical Research: Used in the development of novel, stereochemically-defined pesticides and herbicides.
• Material Science: Potential precursor for chiral polymers or advanced materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic and organometallic chemistry.

Basic Information

Product Name	Phosphine, (2R,1R)-1,2-Cyclopentanediylbis[Dimethyl- (9Ci)
CAS No.	88293-06-5
Molecular Formula	C9H18P2
Molecular Weight	188.19 g/mol
Synonyms	(1R,2R)-1,2-Bis(dimethylphosphino)cyclopentane; (R,R)-1,2-Bis(dimethylphosphino)cyclopentane; (R,R)-Cyclopentane-1,2-diylbis(dimethylphosphine); (R,R)-DCP; (R,R)-BDPC; (R,R)-Me-DuPhos (common ligand class name); DuPhos-type ligand precursor; Chiral bisphosphine ligand.
EINECS	Contact for details

Quality Control

Every batch of our chiral phosphine compounds is produced and tested under stringent quality protocols to ensure high enantiomeric purity and chemical integrity, critical for sensitive asymmetric synthesis. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity (by NMR/HPLC), enantiomeric excess (ee), and impurity profiles. Our quality system supports development from laboratory to pilot scale, ensuring consistent batch-to-batch reproducibility for your R&D and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR / NMR)	Conforms to structure
Purity (by 31P NMR / HPLC)	≥ 95.0%
Enantiomeric Excess (ee)	≥ 98.0% (Typical)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.